A study examing the effect of stopping endocrine therapy of women with breast cancer to allow pregnancy
Weill Cornell Medicine
Trial Summary
In this trial, researchers will study the effects of digital tomosynthesis mammography to see if it's better than digital mammography at breast cancer screening. Digital mammography, also called Full Field Digital Mammography (DM), is a procedure where x-ray is used to product pictures of breast tissues. Digital tomosynthesis mammography, also called Digital Breast Tomography (TM), is similar to DM but it creates a 3D like picture. They are both used to detect if the participant has breast cancer or not. The participants will be randomly assigned into two groups, one group will receive DM, while the other group will receive TM.
Trial Design
518 participants will be recruited and everyone will stop endocrine treatment to allow for pregnancy, and will resume treatment after pregnancy.
Inclusion Criteria
1. 18 to 42 years old inclusive.
2. Have received endocrine therapy.
3. Wish to become pregnant.
4. Are premenopausal.
Exclusion Criteria
1. Are postmenopausal.
2. Currently have breast cancer.
3. Medically unfit to become pregnant.
Exclusion criteria are conditions or characteristics if they apply to you, may likely make you ineligible to participate in the study.
Inclusion criteria is a checklist of items, if they apply to you, may make you eligible to be included for the study.