A study that compares the effectiveness of two different types of partial breast irradiation
NYU Langone Medical Center
Trial Summary
In this trial, researchers will compare the effects of adding lymph node dissection to the standard of care radiation therapy on breast cancer patients. Lymph node dissection is a surgery procedure that looks at lymph nodes, and remove cancer cells if cancer spread from breast to nearby lymph nodes. The population is patients with breast cancer who received chemotherapy and surgery before. The study design is half of the participants will receive lymph node dissection and radiation therapy, while the other half will receive standard of care radiation therapy.
Trial Design
320 participants who have early stage breast cancer will be recruited. About half of the participants will receive partial breast irradiation regimen of 8 GY x 3 days over 5 days, while the other half will receive 6 Gy x 5 over five consecutive days. The assignment will be random.
Inclusion Criteria
1. 50 to 90 years old
2. Must be postmenopausal, for example, at least 2 years without period
3. Have early stage breast cancer
Exclusion Criteria
1. Below 50 years old or above 90 years old
2. Have received radiation therapy before
Exclusion criteria are conditions or characteristics if they apply to you, may likely make you ineligible to participate in the study.
Inclusion criteria is a checklist of items, if they apply to you, may make you eligible to be included for the study.